The executive producer of Supernatural has claimed that Sam and Dean have swapped roles in the new season. Speaking to Entertainment Weekly, Sera Gamble explained that Dean (Jensen Ackles) will now be more reluctant than Sam (Jared Padalecki) to go hunting because of his family.

“When we start the season we very consciously riffed a little bit on season one in that Dean is out of the business and Sam comes for him,” Gamble said. “When we started the series, Sam had attachments. He had a girlfriend he was really serious about, and he had retired from hunting essentially. Dean was this very intense hunter who came for his brother. On the surface anyway, the situation is reversed at the beginning of the season.”

Gamble has previously claimed that the season premiere of Supernatural will focus on Dean. (Source)